Pancreatic cancer has been dubbed a ‘silent killer’ due to how easy it is to overlook the symptoms.
While the death rates of many cancers have dramatically decreased over time, the survival rates for pancreatic cancer are uniquely low.
Part of the problem is that most diagnoses happen after the cancer has already metastasized, or spread. Just 13 per cent of cases are confined to their primary site, according to the National Cancer Institute (NCI).
Cancers like this are difficult to catch in the initial stages as symptoms such as stomach pain and bowel troubles are easily missed or could be attributed to other health problems.
A 2022 survey by the Pancreatic Cancer Action Network found that 83 per cent of adults are unaware of the signs of the disease. Though there is no standard screening method for pancreatic cancer, experts stress that spotting the early symptoms could save lives.
These are five of the early warning signs of the disease:
Jaundice
Jaundice, the yellowing of the skin and eyes, is one of the most common early symptoms of pancreatic cancer.
It’s caused by the build-up a bilirubin, a yellowish-brown substance made by the liver. The liver releases bile, a fluid meant to aid digestion, which contains bilirubin.
In normal liver function, bile moves through ducts into the intestine and helps to break down fats.
However, when bile ducts become blocked, bilirubin builds up, turning the skin and eyes yellow.
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This happens because the pancreas is close to the body’s common bile duct, so tumours press on the duct, even when they are still small and undetectable on scans.
However, tumours on the lower part of the pancreas do not press on the duct until they have spread throughout the organ, which happens in the later stages of the disease.
Pancreatic cancer can also metastasize to the liver.
Other signs of jaundice include dark urine, light-coloured or greasy stools and itchy skin.
Stomach Pain
Cancers that initially form in the body or lower parts of the pancreas can quickly grow large, pressing on nearby organs.
This cancer also presses on the nerves around those organs.
One of the nearby organs is the stomach.
The Pancreatic Action Network estimates that about 70 per cent of patients experience this pain at the time of diagnosis.
At first, it may come and go, getting worse as you lie down or eat. As tumours grow, the pain may become more constant and last longer.
Back Pain
Pain may also radiate from the stomach to the back.
This pain is most often localised to the mid-back, or just below the shoulder blades.
It may also reach the shoulders.
Similar to stomach pain, this is most common when tumours are found in the tail of the pancreas, or the lowest part.